Dioxins (PCDD/PCDFs), and polychlorinated biphenyls (PCBs), still remain of interest to the European Union due to their toxic effects even at very low doses. However, it was only after the so-called “Belgian crisis”, that the European Commission (EC), aiming at a high level of consumers health protection, introduced a number of legal solutions strived at ensuring food and feed safety. The strategy adopted by the European Union allowed for the harmonization of on environmental pollution and the food chain regulatory rules. This article discusses the applicable EU legal regulations regarding dioxins and PCBs in food and feed and the research methods used in the official control of undesirable contaminants.