Dioxins and PCBs are a group of persistent organochlorine compounds widely dispersed in the environment. They are transported by air to every element of the environment and accumulate in biological systems. For wild animals main source of exposure to dioxin and PCBs is the food chain, contaminated plants and soil. The relationship between dioxins (PCDD/Fs) and PCBs in soil, vegetation and wild boar muscles (Sus scrofa) was studied. All samples were collected from industrial and agricultural regions of Poland. High-resolution gas chromatography coupled to high resolution mass spectrometry (HRGC-HRMS) were used for testing. It was found that levels of dioxins and PCBs in the environmental samples and in wild boar muscles were depended on region of origin. PCDD/F/DL-PCB and NDL-PCB soil concentrations were in the range 0.23–8.68 pg WHO-TEQ/g d.m. and 0.06–4.62 ng/g d.m., respectively. In plants mean concentrations of PCDD/F/DL-PCB and NDL-PCB were 0.15–0.85 pg WHO-TEQ/g d.m. and 0.15–0.63 ng/g d.m., respectively. Muscles of boar contained 0.81–3.42 pg WHO-TEQ/g fat of PCDD/F/DL-PCB and NDL-PCB from 4.00 to 12.88 ng/g fat. The correlations between PCDD/F and DL-PCB levels in environmental samples and wild boar muscle were found in all regions. It was confirmed by the Spearman Rank Correlation statistical analysis, the Spearman's rank correlation coefficients (rs) were from 0.51 to 0.92. But ndl-PCB levels in soil and muscles were correlated only in two industrial regions and between leaves and muscles in one agricultural region.